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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC1H1
All Species:
31.82
Human Site:
S4250
Identified Species:
58.33
UniProt:
Q14204
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14204
NP_001367.2
4646
532408
S4250
L
K
T
L
M
A
Q
S
I
Y
G
G
R
V
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112455
4147
474593
V3804
L
S
H
L
K
R
T
V
E
N
I
K
D
P
L
Dog
Lupus familis
XP_537556
4646
532374
S4250
L
K
T
L
M
A
Q
S
I
Y
G
G
R
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHU4
4644
532007
S4248
L
K
T
L
M
A
Q
S
I
Y
G
G
R
V
D
Rat
Rattus norvegicus
P38650
4644
532233
S4248
L
K
T
L
M
A
Q
S
I
Y
G
G
R
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512683
4644
532495
S4248
L
K
T
L
M
A
Q
S
I
Y
G
G
R
V
D
Chicken
Gallus gallus
XP_421371
4617
529846
S4221
L
K
T
L
M
A
Q
S
I
Y
G
G
R
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036210
4643
533172
S4249
L
Q
T
L
M
A
Q
S
I
Y
G
G
R
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
S4234
L
V
T
L
L
S
Q
S
I
Y
G
G
K
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19020
4568
521560
C4198
L
R
T
L
L
S
Q
C
I
Y
G
G
K
I
D
Sea Urchin
Strong. purpuratus
XP_797645
4652
531803
C4247
M
K
T
L
L
S
Q
C
I
Y
G
G
R
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
Y3750
D
L
R
Y
L
W
D
Y
V
T
T
K
S
Y
I
Red Bread Mold
Neurospora crassa
P45443
4367
495560
K4023
F
D
I
V
E
D
L
K
Q
T
V
D
Q
V
S
Conservation
Percent
Protein Identity:
100
N.A.
83.9
99.2
N.A.
99
98.5
N.A.
98.4
95.5
N.A.
90.9
N.A.
71.9
N.A.
55.6
74.5
Protein Similarity:
100
N.A.
84.5
99.6
N.A.
99.4
99.2
N.A.
99.4
97.1
N.A.
95.8
N.A.
85.2
N.A.
73.3
86.2
P-Site Identity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
93.3
N.A.
80
N.A.
66.6
N.A.
60
66.6
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
N.A.
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
49.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
67.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
8
0
0
0
0
8
8
0
70
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
77
77
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
77
0
8
0
0
39
8
% I
% Lys:
0
54
0
0
8
0
0
8
0
0
0
16
16
0
0
% K
% Leu:
77
8
0
85
31
0
8
0
0
0
0
0
0
0
8
% L
% Met:
8
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
77
0
8
0
0
0
8
0
0
% Q
% Arg:
0
8
8
0
0
8
0
0
0
0
0
0
62
0
0
% R
% Ser:
0
8
0
0
0
24
0
62
0
0
0
0
8
0
8
% S
% Thr:
0
0
77
0
0
0
8
0
0
16
8
0
0
0
0
% T
% Val:
0
8
0
8
0
0
0
8
8
0
8
0
0
47
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
77
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _